Franca Schmid

Publications

2026

  • The way of life: The network challenge of blood flow in the brain (Commentary). F Schmid. PNAS. doi: 10.1073/pnas.2537961123
  • Blood Pressure Regulates Functional Coupling of L-Type Ca2+ Channels: Reimaging the Foundation of Cerebral Blood Flow Control. GY Mironova, M MA Baudel, C Lambride, SR Kharche, DA Steven, J Lau, KW MacDougall, M Boulton, F Schmid, MF Navedo, DG Welsh. bioRxiv. doi: 10.64898/2026.03.02.708544v1
  • Evaluation of the diffusion time dependence of the IVIM effect based on realistic capillary flow simulations. F Hennel, MF Lopez, F Schmid. Research Square. doi: 10.21203/rs.3.rs-8722317/v1

2025

  • Loss of Cerebral Autoregulation After Stroke Drives Abnormal Perfusion Patterns. C Lambride, M El Amki, S Wegener, F Schmid. bioRxiv 2025. doi: 10.1101/2025.10.03.680208
  • Impaired capillary-venous drainage contributes to gliosis and demyelination in white matter during aging. S Stamenkovic, F Schmid, G Gurler, F Abolmaali, NA Weitermann, KT Takasaki, SK Bonney, MJ Sosa, HC Bennet, Y Kim, J Waters, AY Shih. Nature Neuroscience. doi: 10.1038/s41593-025-02023-z

2024

  • Leptomeningeal collaterals regulate reperfusion in ischemic stroke. NF Binder, M El Amki, C Glück, W Middleham, AM Reuss, A Bertolo, P Thurner, T Deffieux, C Lambride, R Epp, HL Handelsmann, P Baumgartner, C Orset, P Bethge, Z Kulcsar, A Aguzzi, M Tanter, F Schmid, D Vivien, MT Wyss, A Luft, M Weller, B Weber, S Wegener. Neuron. doi: 10.1016/j.neuron.2024.01.031

2023

  • The role of leptomeningeal collaterals in redistributing blood flow during stroke. R Epp, C Glück, NF Binder, M El Amki, B Weber, S Wegener, P Jenny, F Schmid; PLOS Computational Biology; doi:10.1371/journal.pcbi.1011496
  • Fast convergence strategy for ambiguous inverse problems based on hierarchical regularization. R Epp, F Schmid, P Jenny; Journal of Computational Physics; doi:10.1016/j.jcp.2023.112264

2022

  • Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure. AA Berthiaume, F Schmid, S Stamenkovic, V Coelho-Santos, CD Nielson, B Weber, MW Majesky, AY Shih; Nature Communications; doi:10.1038/s41467-022-33464-w
  • A FACED lift for cerebral blood flow imaging (Commentary). B Weber and F Schmid; PNAS; doi:10.1073/pnas.2207474119
  • Hierarchical regularization of solution ambiguity in underdetermined inverse and optimization problems. R Epp, F Schmid, P Jenny; Journal of Computational Physics: X; doi:10.1016/j.jcpx.2022.100105

2021

  • The severity of microstrokes depends on local vascular topology and baseline perfusion. F Schmid, G Conti, P Jenny, B Weber; eLife; doi:10.7554/eLife.60208
  • Simulation of intravoxel incoherent perfusion signal using a realistic capillary network of a mouse brain. VP Van, F Schmid, G Spinner, S Kozerke, C Federau; NMR in Biomedicine; doi:10.1002/nbm.4528

2020

  • Predicting vessel diameter changes to up-regulate biphasic blood flow during activation in realistic microvascular networks. R Epp, F Schmid, B Weber, P Jenny; Frontiers in Physiology; doi:10.3389/fphys.2020.566303

2019

2017

  • Depth-dependent flow and pressure characteristics in cortical microvascular networks. F Schmid, PS Tsai, D Kleinfeld, P Jenny, B Weber; PLOS Computational Biology; doi:10.1371/journal.pcbi.1005392

2015

  • The impact of capillary dilation on the distribution of red blood cells in artificial networks. F Schmid, J Reichold, B Weber, P Jenny; Am J Physiol Heart and Circ Physiol; doi:10.1152/ajpheart.00335.2014